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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1996-5-28
|
| pubmed:abstractText |
In the course of screening for free radical scavengers, rare metabolites, benzastatins A and B having aminobenzamide skeleton and benzastatins C and D having tetrahydroquinoline skeleton, were isolated from the culture broth of streptomyces nitrosporeus 30643. They showed inhibitory activity against lipid peroxidation in rat liver microsomes. In the cell assay, benzastatins C and D inhibited glutamate toxicity in N18-RE-105 cells with EC50 values of 2.0 and 5.4 microM, respectively.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0021-8820
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
49
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
20-5
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8609080-Animals,
pubmed-meshheading:8609080-Benzamides,
pubmed-meshheading:8609080-Cell Line,
pubmed-meshheading:8609080-Fermentation,
pubmed-meshheading:8609080-Free Radical Scavengers,
pubmed-meshheading:8609080-Glutamic Acid,
pubmed-meshheading:8609080-Lipid Peroxidation,
pubmed-meshheading:8609080-Quinolines,
pubmed-meshheading:8609080-Rats,
pubmed-meshheading:8609080-Streptomyces
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Benzastatins A, B, C, and D: new free radical scavengers from Streptomyces nitrosporeus 30643. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
|
| pubmed:affiliation |
Microbial Chemistry Research Group, Korea Research Institute of Bioscience and Biotechnology, KIST, Yusong, Korea.
|
| pubmed:publicationType |
Journal Article
|