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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1994-3-17
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pubmed:abstractText |
This article reviews the literature on airway healing after lung transplantation. From a historical point of view, this has been the Achilles' heel of lung transplantation through two decades, from the first attempt at single-lung transplantation in 1963 to the clinical successes in the early 1980s. The overall incidence of lethal airway complications is estimated to be 2% to 3%, whereas that of late stricture is 7% to 14%. Comparison of experiences has been difficult without a universal classification; a new classification for airway and anastomotic complications and healing is proposed. Ischemia appears to be the most important factor influencing airway healing. Low-pressure collateral bronchial blood flow from the pulmonary artery may be affected by low cardiac output, reperfusion edema, or rejection; mucosal injury may be further increased by prolonged positive-pressure ventilation. Good bronchial healing appears to be possible without a protective wrap and with early use of steroids. The management of bronchial complications is challenging and requires endoscopic skills including knowledge of endobronchial laser photocoagulation and stent insertion techniques.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0003-4975
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
506-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8311631-Anastomosis, Surgical,
pubmed-meshheading:8311631-Bronchi,
pubmed-meshheading:8311631-Bronchial Diseases,
pubmed-meshheading:8311631-Humans,
pubmed-meshheading:8311631-Lung Transplantation,
pubmed-meshheading:8311631-Necrosis,
pubmed-meshheading:8311631-Postoperative Complications,
pubmed-meshheading:8311631-Wound Healing
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pubmed:year |
1994
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pubmed:articleTitle |
Airway complications in lung transplantation.
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pubmed:affiliation |
Joint Marseille-Montreal Lung Transplant Program, Marseille, France.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|