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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1994-3-9
|
| pubmed:abstractText |
Heart-lung transplantation and lung transplantation have become accepted techniques in adult patients with end-stage cardiopulmonary disease. We report here our experience between July 1985 and March 1993 with 34 children (< 20 years) who underwent heart-lung (n = 18) or lung transplantation (n = 17). Indications for transplantation included cystic fibrosis (n = 9), congenital heart disease with Eisenmenger complex (n = 9), primary pulmonary hypertension (n = 8), pulmonary arteriovenous malformations (n = 2), desquamative interstitial pneumonia (n = 2), Proteus syndrome with multicystic pulmonary disease (n = 1), graft-versus-host disease (n = 1), rheumatoid lung disease (n = 1), and bronchiolitis obliterans and emphysema (n = 1). Twenty-six patients (76%) have survived from 1 to 88 months after transplantation; most patients have returned to an active lifestyle. Of the eight deaths, four were due to infections, two to multiorgan failure, 1 to posttransplant lymphoproliferative disease, and one to donor organ failure. Four of the patients who died had cystic fibrosis. Despite considerable morbidity related to infection, rejection, and function of the heart-lung and lung allograft in some patients, our results with this potentially lifesaving procedure in the pediatric population have been encouraging.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0022-3476
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
124
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
261-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8301434-Adolescent,
pubmed-meshheading:8301434-Adult,
pubmed-meshheading:8301434-Cause of Death,
pubmed-meshheading:8301434-Child,
pubmed-meshheading:8301434-Child, Preschool,
pubmed-meshheading:8301434-Eisenmenger Complex,
pubmed-meshheading:8301434-Female,
pubmed-meshheading:8301434-Follow-Up Studies,
pubmed-meshheading:8301434-Graft Rejection,
pubmed-meshheading:8301434-Heart-Lung Transplantation,
pubmed-meshheading:8301434-Humans,
pubmed-meshheading:8301434-Infant,
pubmed-meshheading:8301434-Infection,
pubmed-meshheading:8301434-Lung Diseases,
pubmed-meshheading:8301434-Lung Transplantation,
pubmed-meshheading:8301434-Male,
pubmed-meshheading:8301434-Postoperative Complications,
pubmed-meshheading:8301434-Survival Analysis
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Experience with pediatric lung transplantation.
|
| pubmed:affiliation |
Children's Hospital of Pittsburgh, Pennsylvania.
|
| pubmed:publicationType |
Journal Article
|