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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1994-10-10
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pubmed:abstractText |
In pinealectomized rats, melatonin receptor density in the suprachiasmatic nuclei was recently shown to be strongly decreased during the dark period. Furthermore, a one-hour long light pulse is able to reverse this dark-induced decrease. We demonstrate here that this effect of a light-pulse during night time is blocked by prior application of the NMDA receptor antagonist MK-801. These results show that the light effect on melatonin receptor density in the SCN is mediated by activation of NMDA-type receptors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
171
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
24-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:8084491-Animals,
pubmed-meshheading:8084491-Dizocilpine Maleate,
pubmed-meshheading:8084491-Light,
pubmed-meshheading:8084491-Male,
pubmed-meshheading:8084491-Melatonin,
pubmed-meshheading:8084491-Pineal Gland,
pubmed-meshheading:8084491-Protein Binding,
pubmed-meshheading:8084491-Rats,
pubmed-meshheading:8084491-Rats, Wistar,
pubmed-meshheading:8084491-Receptors, Cell Surface,
pubmed-meshheading:8084491-Receptors, Melatonin,
pubmed-meshheading:8084491-Suprachiasmatic Nucleus
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pubmed:year |
1994
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pubmed:articleTitle |
The NMDA antagonist MK-801 blocks light effect on melatonin receptor density in rat suprachiasmatic nuclei.
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pubmed:affiliation |
Neurobiologie des Fonctions Rythmiques et Saisonnières', URA-CNRS 1332, Université Louis Pasteur, Strasbourg, France.
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pubmed:publicationType |
Journal Article
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