Source:http://linkedlifedata.com/resource/umls/id/C0065911
MSH: A family of G-protein-coupled receptors that are specific for and mediate the effects of MELATONIN. Activation of melatonin receptors has been associated with decreased intracellular CYCLIC AMP and increased hydrolysis of PHOSPHOINOSITIDES.,NCI: Members of the G protein-coupled superfamily of receptors. Two pharmacologically distinct high affinity melatonin receptors have been identified, Mel1 and Mel2, and Mel1 class receptors Mel1A, Mel1B, and Mel1C have been cloned. Transduce signals via at least two pathways, one inhibiting adenylyl cyclase and the other regulating phospholipide metabolism and calcium concentration.