Linked Life Data

7809512

Source:http://linkedlifedata.com/resource/pubmed/id/7809512

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-1-31
pubmed:abstractText
Fifteen male volunteers, aged 30 to 40 years old, were classified according to body mass index (BMI) as lean (n = 5, BMI less than 20 kg/m2), normal (n = 5, BMI 20-25) or obese (n = 5, BMI over 30). Glucose intolerance was ruled out by a normal oral glucose tolerance test and insulin sensitivity (SI) and glucose effectiveness (SG) were estimated by a minimal model analysis of a frequently sampled intravenous glucose tolerance test modified by an intravenous insulin injection at minute 20. The MINMOD program was fed with 29 or 12 values (reduced sampling schedule). Despite a significant inverse correlation between BMI and SI (r = -0.533 p < 0.05), the latter parameter overlapped among groups and the correlation was lost when obese individuals were not considered. Waist/hip ratio correlated modestly with SI (r = -0.52 p < 0.05). SG did not correlate with BMI. Using the reduced sampling schedule. SI values had a correlation coefficient of 0.78 with those calculated using the usual sampling schedule, although they were 82% lower. We conclude that only a BMI of over 30 accurately predicts a low SI, and that waist/hip ratio does not have a better predictive power.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0034-9887
pubmed:author
pubmed:issnType
Print
pubmed:volume
122
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
241-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[The clinical estimate of adiposity is not a good predictor of insulin tissue sensitivity measured with a minimal model analysis].
pubmed:affiliation
Departamento de Medicina, Facultad de Medicina, Universidad de Chile Hospital José Joaquín Aguirre, Santiago de Chile.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Research Support, Non-U.S. Gov't