| pubmed-article:7730650 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0004096 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0036536 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0036537 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0229664 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0014467 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0079633 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:7730650 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:7730650 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:7730650 | pubmed:dateCreated | 1995-5-31 | lld:pubmed |
| pubmed-article:7730650 | pubmed:abstractText | Eosinophils possess the capacity to synthesize various cytokines. We demonstrate that IL-8 mRNA and protein are constitutively expressed by freshly isolated resting human eosinophils. Most of the patients with bronchial asthma or atopic dermatitis show evidence for up-regulated IL-8 protein expression in eosinophils but not in neutrophils, suggesting that an eosinophil-specific cytokine may act in these patients. To investigate whether the intracellular IL-8 can be released, eosinophils were stimulated by different cytokines and platelet-activating factor. Priming with granulocyte-macrophage CSF and a subsequent 25-min stimulation with RANTES or platelet-activating factor resulted in release of IL-8 from highly purified human eosinophils in vitro. As the eosinophil is the predominant cell in asthmatic inflammation, we determined IL-8 concentrations in bronchoalveolar lavage fluids from normal individuals and asthmatic patients. Bronchoalveolar lavage fluids from patients with bronchial asthma consistently demonstrated high IL-8 concentration compared with the controls. This suggests that IL-8 is released in vivo by inflammatory bronchial cells in asthma. | lld:pubmed |
| pubmed-article:7730650 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7730650 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7730650 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7730650 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7730650 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7730650 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7730650 | pubmed:month | May | lld:pubmed |
| pubmed-article:7730650 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:7730650 | pubmed:author | pubmed-author:BlaserKK | lld:pubmed |
| pubmed-article:7730650 | pubmed:author | pubmed-author:HartungKK | lld:pubmed |
| pubmed-article:7730650 | pubmed:author | pubmed-author:WeberMM | lld:pubmed |
| pubmed-article:7730650 | pubmed:author | pubmed-author:YousefiSS | lld:pubmed |
| pubmed-article:7730650 | pubmed:author | pubmed-author:SimonH UHU | lld:pubmed |
| pubmed-article:7730650 | pubmed:author | pubmed-author:HölzerCC | lld:pubmed |
| pubmed-article:7730650 | pubmed:author | pubmed-author:HemmannSS | lld:pubmed |
| pubmed-article:7730650 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7730650 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:7730650 | pubmed:volume | 154 | lld:pubmed |
| pubmed-article:7730650 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7730650 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7730650 | pubmed:pagination | 5481-90 | lld:pubmed |
| pubmed-article:7730650 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:meshHeading | pubmed-meshheading:7730650-... | lld:pubmed |
| pubmed-article:7730650 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7730650 | pubmed:articleTitle | IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma. | lld:pubmed |
| pubmed-article:7730650 | pubmed:affiliation | Swiss Institute of Allergy and Asthma Research, Davos. | lld:pubmed |
| pubmed-article:7730650 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7730650 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7730650 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7730650 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7730650 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7730650 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7730650 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7730650 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7730650 | lld:pubmed |
