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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-5-24
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pubmed:databankReference | |
pubmed:abstractText |
The human poliovirus (PV) receptor (PVR) is a member of the immunoglobulin (Ig) superfamily with unknown cellular function. We have isolated a human PVR-related (PRR) cDNA. The deduced amino acid (aa) sequence of PRR showed, in the extracellular region, 51.7 and 54.3% similarity with human PVR and with the murine PVR homolog, respectively. The cDNA coding sequence is 1.6-kb long and encodes a deduced 57-kDa protein; this protein has a structural organization analogous to that of PVR, that is, one V- and two C-set Ig domains, with a conserved number of aa. Northern blot analysis indicated that a major 5.9-kb transcript is present in all normal human tissues tested. In situ hybridization showed that the PRR gene is located at bands q23-q24 of human chromosome 11.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
155
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7721102-Amino Acid Sequence,
pubmed-meshheading:7721102-Animals,
pubmed-meshheading:7721102-Base Sequence,
pubmed-meshheading:7721102-Carcinoma,
pubmed-meshheading:7721102-Chromosome Mapping,
pubmed-meshheading:7721102-Chromosomes, Human, Pair 11,
pubmed-meshheading:7721102-Cloning, Molecular,
pubmed-meshheading:7721102-DNA, Complementary,
pubmed-meshheading:7721102-Humans,
pubmed-meshheading:7721102-Membrane Proteins,
pubmed-meshheading:7721102-Mice,
pubmed-meshheading:7721102-Molecular Sequence Data,
pubmed-meshheading:7721102-Receptors, Virus,
pubmed-meshheading:7721102-Sequence Alignment,
pubmed-meshheading:7721102-Tumor Cells, Cultured,
pubmed-meshheading:7721102-Urinary Bladder Neoplasms
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pubmed:year |
1995
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pubmed:articleTitle |
Complementary DNA characterization and chromosomal localization of a human gene related to the poliovirus receptor-encoding gene.
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pubmed:affiliation |
INSERM U.119, Unité de Cancérologie et Thérapeutique Expérimentales, Marseille, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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