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pubmed-article:7536347pubmed:abstractTextTherapy with myeloid colony-stimulating factors has been safely and effectively used in a wide variety of situations associated with neutropenia. We present a case of pseudoleukemia occurring in a patient with lymphoma and pancytopenia after 2 days of treatment with granulocyte colony-stimulating factor (G-CSF). Bone marrow aspirate and flow cytometry study results were consistent with acute myelomonocytic leukemia but were normal after G-CSF was discontinued for 4 days. As previous phase I studies of bone marrow morphology after G-CSF use have not described the extreme myeloid immaturity seen in this patient, it seems likely that the action of G-CSF was enhanced by factors associated with the patient's illness. We emphasize the clinical importance of this case in light of the widespread use of G-CSF.lld:pubmed
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pubmed-article:7536347pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:7536347pubmed:articleTitlePseudoleukemia after granulocyte colony-stimulating factor therapy.lld:pubmed
pubmed-article:7536347pubmed:affiliationDepartment of Internal Medicine, Yale-New Haven Hospital, CT, USA.lld:pubmed
pubmed-article:7536347pubmed:publicationTypeJournal Articlelld:pubmed
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