Granulocyte Colony-Stimulating Factor

Source:http://linkedlifedata.com/resource/umls/id/C0079459

MSH: A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.,NCI: A colony-stimulating factor that stimulates the production of neutrophils (a type of white blood cell). It is a cytokine that is a type of hematopoietic (blood-forming) agent.,NCI: Colony Stimulating Factor 3, encoded by the CSF3 gene, is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different protein isoforms have been found for this gene. (From LocusLink)

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