rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1995-5-12
|
pubmed:abstractText |
Therapy with myeloid colony-stimulating factors has been safely and effectively used in a wide variety of situations associated with neutropenia. We present a case of pseudoleukemia occurring in a patient with lymphoma and pancytopenia after 2 days of treatment with granulocyte colony-stimulating factor (G-CSF). Bone marrow aspirate and flow cytometry study results were consistent with acute myelomonocytic leukemia but were normal after G-CSF was discontinued for 4 days. As previous phase I studies of bone marrow morphology after G-CSF use have not described the extreme myeloid immaturity seen in this patient, it seems likely that the action of G-CSF was enhanced by factors associated with the patient's illness. We emphasize the clinical importance of this case in light of the widespread use of G-CSF.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0038-4348
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
88
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
462-4
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7536347-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:7536347-Bone Marrow,
pubmed-meshheading:7536347-Cyclophosphamide,
pubmed-meshheading:7536347-Doxorubicin,
pubmed-meshheading:7536347-Etoposide,
pubmed-meshheading:7536347-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:7536347-Humans,
pubmed-meshheading:7536347-Leukemia, Myelomonocytic, Acute,
pubmed-meshheading:7536347-Lymphoma, Large B-Cell, Diffuse,
pubmed-meshheading:7536347-Male,
pubmed-meshheading:7536347-Middle Aged,
pubmed-meshheading:7536347-Neoplasms, Second Primary,
pubmed-meshheading:7536347-Neutropenia,
pubmed-meshheading:7536347-Prednisone,
pubmed-meshheading:7536347-Vincristine
|
pubmed:year |
1995
|
pubmed:articleTitle |
Pseudoleukemia after granulocyte colony-stimulating factor therapy.
|
pubmed:affiliation |
Department of Internal Medicine, Yale-New Haven Hospital, CT, USA.
|
pubmed:publicationType |
Journal Article,
Case Reports
|