Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-11-26
|
pubmed:abstractText |
The effects of sucralfate ingestion on serum and specific tissue aluminum (Al) accumulation were studied in normal rats fed either a control diet or the same diet supplemented with sucralfate. Although serum Al concentrations were not significantly different between the groups, animals fed sucralfate for 8 weeks had significantly higher bone but not brain or liver Al concentrations when compared with controls. This study indicates that 8 weeks exposure to Al in sucralfate leads to an increase in bone Al concentrations, without changes in serum Al concentrations, suggesting that serum Al concentration may be a poor predictor of gastrointestinal absorption and specific tissue retention of Al.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0731-3810
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
87-93
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6548526-Absorption,
pubmed-meshheading:6548526-Administration, Oral,
pubmed-meshheading:6548526-Aluminum,
pubmed-meshheading:6548526-Animals,
pubmed-meshheading:6548526-Blood Urea Nitrogen,
pubmed-meshheading:6548526-Calcium,
pubmed-meshheading:6548526-Male,
pubmed-meshheading:6548526-Phosphorus,
pubmed-meshheading:6548526-Rats,
pubmed-meshheading:6548526-Rats, Inbred Strains,
pubmed-meshheading:6548526-Sucralfate,
pubmed-meshheading:6548526-Tissue Distribution
|
pubmed:year |
1984
|
pubmed:articleTitle |
The effects of sucralfate ingestion on serum and specific tissue aluminum concentration in normal rats.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|