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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-12-18
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pubmed:abstractText |
Sn-protoporphyrin is a potent competitive inhibitor of heme oxygenase, can suppress neonatal and other forms of hyperbilirubinemia in laboratory animals, and represents a potential new approach to the treatment of neonatal jaundice in humans. In order to study the disposition of Sn-protoporphyrin in vivo we have developed a sensitive fluorometric method for the quantitation of this metalloporphyrin in biological samples. The method is sensitive to concentrations as low as 0.01 nmol/ml, and is specific for Sn-protoporphyrin even in the presence of other porphyrins such as protoporphyrin.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0003-2697
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
213-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6496929-Animals,
pubmed-meshheading:6496929-Feces,
pubmed-meshheading:6496929-Humans,
pubmed-meshheading:6496929-Male,
pubmed-meshheading:6496929-Metalloporphyrins,
pubmed-meshheading:6496929-Porphyrins,
pubmed-meshheading:6496929-Protoporphyrins,
pubmed-meshheading:6496929-Rats,
pubmed-meshheading:6496929-Rats, Inbred Strains,
pubmed-meshheading:6496929-Solutions,
pubmed-meshheading:6496929-Spectrometry, Fluorescence
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pubmed:year |
1984
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pubmed:articleTitle |
Fluorometric measurement of tin-protoporphyrin in biological samples.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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