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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1987-1-2
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pubmed:databankReference | |
pubmed:abstractText |
cDNAs encoding the mouse insulin-like growth factor II (IGF-II) precursor have been isolated from a placental library and sequenced. Mouse prepro-IGF-II is predicted to be 180 amino acids and has 84% and 97% identity with human and rat IGF-II precursors, respectively. There are two prepro-IGF-II transcripts in mouse placenta; the major transcript is 3850 bases and the minor one is 4800 bases. Prepro-IGF-II mRNA cannot be detected in adult mouse liver, but it is readily detected in adult human liver, indicating that there are differences in the regulation of expression of the IGF-II gene in the liver of adult mice and human beings.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0198-0238
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
357-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3780370-Animals,
pubmed-meshheading:3780370-Base Sequence,
pubmed-meshheading:3780370-Cloning, Molecular,
pubmed-meshheading:3780370-DNA,
pubmed-meshheading:3780370-Insulin-Like Growth Factor II,
pubmed-meshheading:3780370-Mice,
pubmed-meshheading:3780370-Placenta,
pubmed-meshheading:3780370-Protein Precursors,
pubmed-meshheading:3780370-Sequence Homology, Nucleic Acid,
pubmed-meshheading:3780370-Somatomedins
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pubmed:year |
1986
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pubmed:articleTitle |
Sequence of a placental cDNA encoding the mouse insulin-like growth factor II precursor.
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pubmed:publicationType |
Journal Article,
Comparative Study
|