Linked Life Data

3323152

Source:http://linkedlifedata.com/resource/pubmed/id/3323152

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1988-3-2
pubmed:abstractText
The herniation of the nucleus pulposus into the vertebral body produces ectopic deposit of disc material which are known as Schmorl's nodes. This prolapsed disc tissue leaves characteristic deformations on the surface of the vertebral body and hence the incidence of this lesion can be studied in skeletal remains. This report describes the occurrence of Schmorl's nodes in TV8-SV1 in two historic adult British populations, one from Aberdeen and the other from London. In the Aberdeen group, both males and females showed a high incidence rate and severity of Schmorl's nodes. In the London group, the males had a similarly high affliction whereas the females were nearly free of the condition. The lesion had no significant predilection for any one particular vertebral surface. However, in males in both localities, the frequency of Schmorl's nodes was significantly higher in the thoracic region than in the lumbosacral region. In contrast, both groups of females showed similar node frequency in these two zones. The majority of Schmorl's nodes were localised in the central and central-posterior regions of the vertebral surface. When nodes occurred on successive vertebral surfaces, they often formed sequences showing similar shape and position. The aetiology of Schmorl's nodes is unclear. Various hypothetical causal factors were appraised in relation to the findings of this study. It was suggested that anomalies in vascular and/or notochordal regression may be related to the development of the lesion.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0021-8782
pubmed:author
pubmed:issnType
Print
pubmed:volume
145
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-96
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Schmorl's nodes (intravertebral herniations of intervertebral disc tissue) in two historic British populations.
pubmed:affiliation
Department of Anatomy, Marischal College, University of Aberdeen, Scotland.
pubmed:publicationType
Journal Article, Historical Article, Research Support, Non-U.S. Gov't