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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0010068,
umls-concept:C0014766,
umls-concept:C0023822,
umls-concept:C0030705,
umls-concept:C0032659,
umls-concept:C0205160,
umls-concept:C0205250,
umls-concept:C0205307,
umls-concept:C0370003,
umls-concept:C0683149,
umls-concept:C0750502,
umls-concept:C1522609,
umls-concept:C1554112,
umls-concept:C1608376,
umls-concept:C1707520,
umls-concept:C2347026
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pubmed:issue |
3
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pubmed:dateCreated |
1987-10-19
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pubmed:abstractText |
In a previous clinical study it was found that patients with coronary heart disease and diabetics with peripheral artery disease often have an elevated erythrocyte aggregation value (AW) and that there is a positive correlation between AW and the number of risk factors found in a subject. In the present investigation we studied the relationship between AW and the serum concentration of high density lipoprotein cholesterol (HDL-C), which is known to be inversely associated with coronary heart disease (CHD) incidence. We found highly significant negative correlations between AW and HDL-C both in a subsample of the study population of a cross-sectional epidemiologic study on CHD risk factors (First Survey of the MONICA Project Augsburg) and in male patients with angiographically confirmed CHD. Correlation coefficients were -0.233 for normal men (P less than 0.01, n = 136), -0.261 for normal women (P less than 0.01, n = 117), and -0.745 for CHD patients (P less than 0.01, n = 14). The results support the concept that the erythrocyte aggregation value as an indicator of cardiovascular risk is consistent with established risk factor associations.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0014-2972
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
275-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3113972-Adult,
pubmed-meshheading:3113972-Cholesterol, HDL,
pubmed-meshheading:3113972-Coronary Disease,
pubmed-meshheading:3113972-Erythrocyte Aggregation,
pubmed-meshheading:3113972-Female,
pubmed-meshheading:3113972-Humans,
pubmed-meshheading:3113972-Male,
pubmed-meshheading:3113972-Middle Aged
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pubmed:year |
1987
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pubmed:articleTitle |
Highly significant negative correlations between erythrocyte aggregation value and serum concentration of high density lipoprotein cholesterol in a sample from a normal population and in patients with coronary heart disease.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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