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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1989-3-23
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pubmed:abstractText |
Excitatory amino acid receptors in the neonatal rat hippocampus have opposing actions on phosphoinositide (PI) metabolism. Quisqualic acid (QA), but not the QA receptor agonist AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid), potently stimulates inositol phosphate (IP) formation. Activation of NMDA (N-methyl-D-aspartate) receptors inhibits the QA-induced stimulation by 70% by a mechanism which is dependent on extracellular calcium.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Aspartic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorides,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamates,
http://linkedlifedata.com/resource/pubmed/chemical/Ibotenic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Kainic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Lithium,
http://linkedlifedata.com/resource/pubmed/chemical/Lithium Chloride,
http://linkedlifedata.com/resource/pubmed/chemical/N-Methylaspartate,
http://linkedlifedata.com/resource/pubmed/chemical/Oxadiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositols,
http://linkedlifedata.com/resource/pubmed/chemical/Quisqualic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, AMPA,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glutamate,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, N-Methyl-D-Aspartate,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Neurotransmitter,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrodotoxin,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Amino-3-hydroxy-5-methyl-4-iso...
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-8993
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
464
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2905924-Animals,
pubmed-meshheading:2905924-Aspartic Acid,
pubmed-meshheading:2905924-Chlorides,
pubmed-meshheading:2905924-Glutamates,
pubmed-meshheading:2905924-Hippocampus,
pubmed-meshheading:2905924-Ibotenic Acid,
pubmed-meshheading:2905924-Kainic Acid,
pubmed-meshheading:2905924-Lithium,
pubmed-meshheading:2905924-Lithium Chloride,
pubmed-meshheading:2905924-N-Methylaspartate,
pubmed-meshheading:2905924-Oxadiazoles,
pubmed-meshheading:2905924-Phosphatidylinositols,
pubmed-meshheading:2905924-Quisqualic Acid,
pubmed-meshheading:2905924-Rats,
pubmed-meshheading:2905924-Rats, Inbred Strains,
pubmed-meshheading:2905924-Receptors, AMPA,
pubmed-meshheading:2905924-Receptors, Glutamate,
pubmed-meshheading:2905924-Receptors, N-Methyl-D-Aspartate,
pubmed-meshheading:2905924-Receptors, Neurotransmitter,
pubmed-meshheading:2905924-Tetrodotoxin,
pubmed-meshheading:2905924-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
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pubmed:year |
1988
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pubmed:articleTitle |
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
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pubmed:affiliation |
Department of Psychobiology, University of California, Irvine 92717.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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