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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1989-6-12
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pubmed:abstractText |
It is now well established that cytokines are involved in the regulation of gene expression from HIV-1 LTR. The present study provides evidence that TNF-alpha stimulates HIV-1 gene expression and that the enhancer sequence within the HIV-1 LTR is involved in the stimulation. These results support the idea that immunologic stimulation and infection may trigger the development of clinical AIDS in individuals latently infected with HIV-1.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0889-2229
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
131-8
|
pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2713164-Animals,
pubmed-meshheading:2713164-Chloramphenicol O-Acetyltransferase,
pubmed-meshheading:2713164-Enhancer Elements, Genetic,
pubmed-meshheading:2713164-Gene Expression Regulation,
pubmed-meshheading:2713164-HIV-1,
pubmed-meshheading:2713164-Humans,
pubmed-meshheading:2713164-Plasmids,
pubmed-meshheading:2713164-RNA, Messenger,
pubmed-meshheading:2713164-RNA, Viral,
pubmed-meshheading:2713164-Transfection,
pubmed-meshheading:2713164-Tumor Necrosis Factor-alpha
|
pubmed:year |
1989
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pubmed:articleTitle |
Augmentation of human immunodeficiency virus type 1 gene expression by tumor necrosis factor alpha.
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pubmed:affiliation |
Virology Division, National Cancer Center Research Institute, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|