Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-4-25
pubmed:abstractText
The effects of a 2.5-h running test on the plasma concentrations of elastase-alpha 1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor were evaluated in eight healthy young male subjects. Neopterin was measured by radioimmunoassay, elastase-alpha 1-antitrypsin, tumor necrosis factor, and soluble interleukin-2 receptor by enzyme immunoassay. The post-exercise values were corrected for plasma volume changes which were calculated from hematocrit and hemoglobin values. Compared with the concentrations before exercise, elastase-alpha 1-antitrypsin values were significantly increased during the run (1 h after the start) (P less than 0.01) as well as during the first few hours after the end of the running test (P less than 0.01). A significant increase of tumor necrosis factor and neopterin was observed 1 h after the end and 1,3, and 24 h after the end of the running test, respectively, (P less than 0.01), and soluble interleukin-2 receptor concentrations were significantly elevated 1 and 2 days after exercise (P less than 0.01). The increase of elastase-alpha 1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor supports the concept of a functional involvement of polymorphonuclear neutrophils and an activation of macrophages and T-lymphocytes after prolonged exercise.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0172-4622
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
434-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Plasma elastase-alpha 1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor after prolonged exercise.
pubmed:affiliation
Institut für Kreislaufforschung und Sportmedizin, Deutsche Sporthochschule Köln, FRG.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't