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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1988-9-8
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pubmed:abstractText |
An immunocytochemical assay using monoclonal anti-progesterone receptor (PR-ICA) was performed in nonmalignant (N = 57) and malignant (N = 200) breast disorders. The results were analyzed with a computerized system of image analysis referred to as SAMBA and correlated with binding assays (DCC), and with standard histopathologic findings. It was shown that there was a correlation between 1) the PR-ICA and the binding assays (91.5%), and 2) between the binding assays and the multiparametric computerized (SAMBA) analysis of the PR-ICA. It was also shown that SAMBA provides an accurate, reliable, and reproducible evaluation of PR-ICA that is complementary to binding assays and constitutes a standardized method of evaluating the heterogeneity of the progesterone receptor (PR) distribution in tumors. It is concluded that SAMBA analysis of both the PR-ICA and estrogen receptor (ER-ICA) should improve the prognostic evaluation and the prediction of responsiveness to endocrine therapy in breast carcinomas.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-13499785,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-164730,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-230330,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-2436753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-2449956,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-2997552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3514427,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3522449,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3567371,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3778611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3791214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3792707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3814295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-385473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3888366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3893573,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3965140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-3978544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-535122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6095669,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6130702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6193072,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6251517,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6284085,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6290045,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6317982,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6348406,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6508034,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6724571,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-6995487,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-7045307,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-7054272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-7054273,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-7427948,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2456699-922747
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0002-9440
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
132
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-211
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2456699-Antibodies, Monoclonal,
pubmed-meshheading:2456699-Breast,
pubmed-meshheading:2456699-Breast Diseases,
pubmed-meshheading:2456699-Breast Neoplasms,
pubmed-meshheading:2456699-Female,
pubmed-meshheading:2456699-Humans,
pubmed-meshheading:2456699-Image Processing, Computer-Assisted,
pubmed-meshheading:2456699-Immunochemistry,
pubmed-meshheading:2456699-Receptors, Estrogen,
pubmed-meshheading:2456699-Receptors, Progesterone,
pubmed-meshheading:2456699-Staining and Labeling,
pubmed-meshheading:2456699-Tissue Distribution
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pubmed:year |
1988
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pubmed:articleTitle |
Multiparametric analysis (SAMBA 200) of the progesterone receptor immunocytochemical assay in nonmalignant and malignant breast disorders.
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pubmed:affiliation |
Pathology Department, Centre Hospitalo-Universitaire Timone, Marseille, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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