Linked Life Data

2187367

Source:http://linkedlifedata.com/resource/pubmed/id/2187367

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pubmed-article:2187367pubmed:abstractTextTo further characterize HIV-1 and HIV-2 Western blot indeterminate (IWB) sera, 402 sera from 318 healthy low-risk individuals from West Virginia and 159 African sera obtained in the pre-AIDS era (1968-1972) were studied. All IWB sera tested for antigen by HIV-1 enzyme immunoassay (EIA-Ag) were negative. HIV-1 and HIV-2 IWB reactivity occurred independent of HIV-1 and HIV-2 false-positive testing for antibody by enzyme immunoassay (EIA-Ab) and no cross-reactions between HIV-1 and HIV-2 IWB patterns were detected. The IWB patterns were reproducible, demonstrated no age or sex related pattern, and showed no evidence of vertical or horizontal transmission. The African sera exhibited a significantly higher number of IWB patterns. IWB reactivity in HIV-1 and HIV-2 seronegative individuals may not be viral in origin and the occurrence of IWB pattern may vary among populations.lld:pubmed
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pubmed-article:2187367pubmed:articleTitleOccurrence, characteristics, and patterns of HIV-1 and HIV-2 western blot indeterminate sera in low risk populations in West Virginia and pre-AIDS Africa.lld:pubmed
pubmed-article:2187367pubmed:affiliationMarshall University School of Medicine, Huntington, West Virginia.lld:pubmed
pubmed-article:2187367pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2187367pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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