Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1990-6-20
|
| pubmed:abstractText |
To further characterize HIV-1 and HIV-2 Western blot indeterminate (IWB) sera, 402 sera from 318 healthy low-risk individuals from West Virginia and 159 African sera obtained in the pre-AIDS era (1968-1972) were studied. All IWB sera tested for antigen by HIV-1 enzyme immunoassay (EIA-Ag) were negative. HIV-1 and HIV-2 IWB reactivity occurred independent of HIV-1 and HIV-2 false-positive testing for antibody by enzyme immunoassay (EIA-Ab) and no cross-reactions between HIV-1 and HIV-2 IWB patterns were detected. The IWB patterns were reproducible, demonstrated no age or sex related pattern, and showed no evidence of vertical or horizontal transmission. The African sera exhibited a significantly higher number of IWB patterns. IWB reactivity in HIV-1 and HIV-2 seronegative individuals may not be viral in origin and the occurrence of IWB pattern may vary among populations.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0002-9637
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
42
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
460-4
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2187367-Adolescent,
pubmed-meshheading:2187367-Adult,
pubmed-meshheading:2187367-Age Factors,
pubmed-meshheading:2187367-Blotting, Western,
pubmed-meshheading:2187367-Child,
pubmed-meshheading:2187367-Child, Preschool,
pubmed-meshheading:2187367-False Positive Reactions,
pubmed-meshheading:2187367-Female,
pubmed-meshheading:2187367-HIV Antibodies,
pubmed-meshheading:2187367-HIV Seropositivity,
pubmed-meshheading:2187367-HIV-1,
pubmed-meshheading:2187367-HIV-2,
pubmed-meshheading:2187367-Humans,
pubmed-meshheading:2187367-Immunoenzyme Techniques,
pubmed-meshheading:2187367-Infant,
pubmed-meshheading:2187367-Kenya,
pubmed-meshheading:2187367-Liberia,
pubmed-meshheading:2187367-Male,
pubmed-meshheading:2187367-Risk Factors,
pubmed-meshheading:2187367-Sex Factors,
pubmed-meshheading:2187367-West Virginia,
pubmed-meshheading:2187367-Zimbabwe
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Occurrence, characteristics, and patterns of HIV-1 and HIV-2 western blot indeterminate sera in low risk populations in West Virginia and pre-AIDS Africa.
|
| pubmed:affiliation |
Marshall University School of Medicine, Huntington, West Virginia.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|