Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2011-3-28
pubmed:abstractText
There are currently no recommendations indicating when stimulation should begin after autologous peripheral blood stem cell transplantation (PBSCT). We compared the outcome following between two treatment groups, in which daily granulocyte colony stimulating factor (G-CSF) administration began on either the fifth or the eighth day after PBSCT in lymphoma and myeloma patients. We studied eight clinical parameters: number of G-CSF injections, number of days of hospitalization, of red blood cell or platelet transfusions; days when body temperature exceeds 38°C; days of parenteral nutrition; weight loss and hospitalization costs. We studied also four biological parameters: number of CD34+ cells, days with leucocytes less than 1 × 10(9) /L, days with hemoglobin less than 90 g/L or with less than 50 × 10(9) /L of platelets. There were no statistical significant differences between the study arms. It seems that delayed stimulation by G-CSF after PBSCT is safety and does not seem to modify bone marrow recovery timing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1096-8652
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
351-2
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:21442638-Adult, pubmed-meshheading:21442638-Aged, pubmed-meshheading:21442638-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:21442638-Bone Marrow, pubmed-meshheading:21442638-Combined Modality Therapy, pubmed-meshheading:21442638-Drug Administration Schedule, pubmed-meshheading:21442638-Granulocyte Colony-Stimulating Factor, pubmed-meshheading:21442638-Hematopoietic Stem Cell Mobilization, pubmed-meshheading:21442638-Humans, pubmed-meshheading:21442638-Lymphoma, pubmed-meshheading:21442638-Middle Aged, pubmed-meshheading:21442638-Multiple Myeloma, pubmed-meshheading:21442638-Peripheral Blood Stem Cell Transplantation, pubmed-meshheading:21442638-Recombinant Proteins, pubmed-meshheading:21442638-Time Factors, pubmed-meshheading:21442638-Transplantation Conditioning, pubmed-meshheading:21442638-Treatment Outcome
pubmed:year
2011
pubmed:articleTitle
Delayed G-CSF stimulation after PBSCT does not seem to modify the biological parameters of bone marrow recovery.
pubmed:affiliation
Department of Clinical Hematology, Institute of Oncology and Hematology, Hopital Morvan, CHRU Brest, France. jcianotto@hotmail.com
pubmed:publicationType
Journal Article