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pubmed-article:21425122pubmed:abstractTextThe origin of the mesenchymal cells responsible for the intimal fibrosis in systemic sclerosis (SSc) has not been fully identified. The present study was undertaken to investigate whether subendothelial mesenchymal cells may emerge through transdifferentiation of endothelial cells (ECs) into myofibroblasts via endothelial-mesenchymal transition (EndoMT) in vitro and to explore the signaling pathways involved in this process.lld:pubmed
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pubmed-article:21425122pubmed:authorpubmed-author:JimenezSergio...lld:pubmed
pubmed-article:21425122pubmed:authorpubmed-author:LiZhaodongZlld:pubmed
pubmed-article:21425122pubmed:copyrightInfoCopyright © 2011 by the American College of Rheumatology.lld:pubmed
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pubmed-article:21425122pubmed:volume63lld:pubmed
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pubmed-article:21425122pubmed:articleTitleProtein kinase C? and c-Abl kinase are required for transforming growth factor ? induction of endothelial-mesenchymal transition in vitro.lld:pubmed
pubmed-article:21425122pubmed:affiliationThomas Jefferson University, Philadelphia, Pennsylvania, USA.lld:pubmed
pubmed-article:21425122pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21425122pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed