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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0019612,
umls-concept:C0025543,
umls-concept:C0026336,
umls-concept:C0205263,
umls-concept:C0332307,
umls-concept:C0428791,
umls-concept:C0596901,
umls-concept:C1171362,
umls-concept:C1186983,
umls-concept:C1412828,
umls-concept:C1515670,
umls-concept:C2004457,
umls-concept:C2599702
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pubmed:issue |
1
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pubmed:dateCreated |
2011-6-20
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pubmed:abstractText |
Matrix metalloproteinases participate in remodeling of extracellular matrix, which is central to the development of aortic stenosis. Synthesis of certain matrix metalloproteinases is induced by the glycoprotein extracellular matrix metalloproteinase inducer. We investigated whether extracellular matrix metalloproteinase inducer and membrane-type 1 matrix metalloproteinase are abundant in calcific aortic valve and their role in the pathogenesis of this condition.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1097-685X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
142
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
191-8
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pubmed:meshHeading |
pubmed-meshheading:21146836-Antigens, CD147,
pubmed-meshheading:21146836-Aortic Valve,
pubmed-meshheading:21146836-Aortic Valve Stenosis,
pubmed-meshheading:21146836-Blotting, Western,
pubmed-meshheading:21146836-Calcinosis,
pubmed-meshheading:21146836-Cardiomyopathies,
pubmed-meshheading:21146836-Cells, Cultured,
pubmed-meshheading:21146836-Coculture Techniques,
pubmed-meshheading:21146836-Humans,
pubmed-meshheading:21146836-Immunohistochemistry,
pubmed-meshheading:21146836-Macrophages,
pubmed-meshheading:21146836-Matrix Metalloproteinase 14,
pubmed-meshheading:21146836-RNA Interference,
pubmed-meshheading:21146836-Transendothelial and Transepithelial Migration
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pubmed:year |
2011
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pubmed:articleTitle |
Extracellular matrix metalloproteinase inducer (CD147) and membrane type 1-matrix metalloproteinase are expressed on tissue macrophages in calcific aortic stenosis and induce transmigration in an artificial valve model.
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pubmed:affiliation |
Deutsches Herzzentrum und I Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, München, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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