Source:http://linkedlifedata.com/resource/pubmed/id/20665488
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
|
pubmed:dateCreated |
2010-11-8
|
pubmed:abstractText |
It has not been well established whether genetic variations can be biomarkers for clinical outcome of gemcitabine therapy. The purpose of this study was to identify single nucleotide polymorphisms (SNPs) of gemcitabine metabolic and transporter genes that are associated with toxicity and efficacy of gemcitabine-based therapy in patients with locally advanced pancreatic cancer.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0008-543X
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 American Cancer Society.
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
116
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
5325-35
|
pubmed:dateRevised |
2011-10-5
|
pubmed:meshHeading |
pubmed-meshheading:20665488-Aged,
pubmed-meshheading:20665488-Deoxycytidine,
pubmed-meshheading:20665488-Disease-Free Survival,
pubmed-meshheading:20665488-Eukaryotic Initiation Factor-3,
pubmed-meshheading:20665488-Female,
pubmed-meshheading:20665488-Gene Expression Profiling,
pubmed-meshheading:20665488-Genotype,
pubmed-meshheading:20665488-Humans,
pubmed-meshheading:20665488-Male,
pubmed-meshheading:20665488-Middle Aged,
pubmed-meshheading:20665488-Pancreatic Neoplasms,
pubmed-meshheading:20665488-Polymorphism, Single Nucleotide
|
pubmed:year |
2010
|
pubmed:articleTitle |
Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer.
|
pubmed:affiliation |
Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA. dli@mdanderson.org
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|