Source:http://linkedlifedata.com/resource/pubmed/id/20478282
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
17-18
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| pubmed:dateCreated |
2010-7-12
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| pubmed:abstractText |
Methionine (Met) is a key metabolite used in the newborn screening of homocystinuria by tandem mass spectrometry (MS/MS). Recently, a loss of ion counts in both Met and its deuterium-labeled internal standard ((2)H(3)-Met) was observed by the CDC's Newborn Screening Quality Assurance Program laboratory. We report on the stability of labeled and unlabeled Met solutions and their storage in two types of 96 well microtiter plates to illustrate the potential loss of Met following storage of samples prior to MS/MS analysis.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Sep
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| pubmed:issn |
1873-3492
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2010 Elsevier B.V. All rights reserved.
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| pubmed:issnType |
Electronic
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| pubmed:day |
6
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| pubmed:volume |
411
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1284-6
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| pubmed:meshHeading |
pubmed-meshheading:20478282-Humans,
pubmed-meshheading:20478282-Infant, Newborn,
pubmed-meshheading:20478282-Methionine,
pubmed-meshheading:20478282-Neonatal Screening,
pubmed-meshheading:20478282-Reference Standards,
pubmed-meshheading:20478282-Specimen Handling,
pubmed-meshheading:20478282-Tandem Mass Spectrometry
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| pubmed:year |
2010
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| pubmed:articleTitle |
Potential loss of methionine following extended storage of newborn screening samples prepared for tandem mass spectrometry analysis.
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| pubmed:affiliation |
Pediatrix Analytical, The Center for Research and Education, Pediatrix Medical Group, Inc., 1301 Concord Terrace, Sunrise, FL 33323, USA. donald_chace@pediatrix.com
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|