Source:http://linkedlifedata.com/resource/pubmed/id/20467161
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2010-9-8
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pubmed:abstractText |
IgG4-positive plasma cell infiltration into multiple organs or tissues, such as the pancreas and salivary glands, associated with increased serum levels of IgG4 is a characteristic finding seen in IgG4-related disease. Affected organs may appear tumorous as a result of chronic inflammatory processes accompanied with progressive fibrosis. Recent cases of this disorder in which the pituitary gland was affected include cases of diffuse enlargement of the pituitary and/or its stalk associated with central diabetes insipidus and/or impaired anterior hormone production. Here we report two such cases, as well as two additional previously undiagnosed cases found in our database. In order to make a correct diagnosis of pituitary lesion involvement with IgG4-related disease, the clinical background and concomitant disorders should be carefully taken into consideration and the measurement of serum levels of IgG4 seems to be useful.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1348-4540
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
719-25
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pubmed:meshHeading |
pubmed-meshheading:20467161-Aged,
pubmed-meshheading:20467161-Diabetes Insipidus,
pubmed-meshheading:20467161-Diagnosis, Differential,
pubmed-meshheading:20467161-Female,
pubmed-meshheading:20467161-Humans,
pubmed-meshheading:20467161-Hypopituitarism,
pubmed-meshheading:20467161-Immunoglobulin G,
pubmed-meshheading:20467161-Magnetic Resonance Imaging,
pubmed-meshheading:20467161-Male,
pubmed-meshheading:20467161-Pituitary Hormones,
pubmed-meshheading:20467161-Prednisolone
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pubmed:year |
2010
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pubmed:articleTitle |
Putative IgG4-related pituitary disease with hypopituitarism and/or diabetes insipidus accompanied with elevated serum levels of IgG4.
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pubmed:affiliation |
First Department of Medicine, Nagasaki University School of Medicine, Nagasaki, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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