|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
15
|
|
pubmed:dateCreated |
2010-10-25
|
|
pubmed:abstractText |
There is a decreased serotonergic function in impulsive aggression and borderline personality disorder (BPD), and genetic association studies suggest a role of serotonergic genes in impulsive aggression and BPD. Only one study has analyzed the association between the tryptophan-hydroxylase 2 (TPH2) gene and BPD. A TPH2 "risk" haplotype has been described that is associated with anxiety, depression and suicidal behavior.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1879-1379
|
|
pubmed:author |
pubmed-author:BevilacquaLauraL,
pubmed-author:GoldmanDavidD,
pubmed-author:GoodmanMarianneM,
pubmed-author:HodgkinsonColinC,
pubmed-author:KoenigsbergHarold WHW,
pubmed-author:NewAntonia SAS,
pubmed-author:Perez-RodriguezM MercedesMM,
pubmed-author:SieverLarry JLJ,
pubmed-author:WeinsteinShaunaS,
pubmed-author:YuanQiaopingQ,
pubmed-author:ZhouZhifengZ
|
|
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
44
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1075-81
|
|
pubmed:dateRevised |
2011-11-1
|
|
pubmed:meshHeading |
pubmed-meshheading:20451217-Adult,
pubmed-meshheading:20451217-Aggression,
pubmed-meshheading:20451217-Borderline Personality Disorder,
pubmed-meshheading:20451217-Ethnic Groups,
pubmed-meshheading:20451217-European Continental Ancestry Group,
pubmed-meshheading:20451217-Female,
pubmed-meshheading:20451217-Gene Frequency,
pubmed-meshheading:20451217-Genetic Predisposition to Disease,
pubmed-meshheading:20451217-Genome-Wide Association Study,
pubmed-meshheading:20451217-Haplotypes,
pubmed-meshheading:20451217-Humans,
pubmed-meshheading:20451217-Male,
pubmed-meshheading:20451217-Middle Aged,
pubmed-meshheading:20451217-Polymorphism, Single Nucleotide,
pubmed-meshheading:20451217-Questionnaires,
pubmed-meshheading:20451217-Sex Factors,
pubmed-meshheading:20451217-Suicide, Attempted,
pubmed-meshheading:20451217-Tryptophan Hydroxylase
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls.
|
|
pubmed:affiliation |
Department of Psychiatry, Mount Sinai School of Medicine, Psychiatry Box # 1230, One Gustave L. Levy Place, New York, NY 10029, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
|
