Linked Life Data

20209249

Source:http://linkedlifedata.com/resource/pubmed/id/20209249

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-3-8
pubmed:abstractText
The in vivo mechanics of the annulus fibrosus of the intervertebral disc is one of biaxial rather than uniaxial loading. The material properties of the annulus are intimately linked to the osmolarity in the tissue. This paper presents biaxial relaxation experiments of canine annulus fibrosus tissue under stepwise changes of external salt concentration. The force tracings show that stresses are strongly dependent on time, salt concentration and orientation. The force tracing signature of a response to a change in strain, is one of a jump in stress that relaxes partly as the new strain is maintained. The force tracing signature of a stepwise change in salt concentration is a progressive monotonous change in stress towards a new equilibrium value. Although the number of samples does not allow any definitive quantitative conclusions, the trends may shed light on the complex interaction among the directionality of forces, strains and fiber orientation on one hand, and on the other hand, the osmolarity of the tissue. The dual response to a change in strain is understood as an immediate response before fluid flows in or out of the tissue, followed by a progressive readjustment of the fluid content in time because of the gradient in fluid chemical potential between the tissue and the surrounding solution.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1678-2690
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-51
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Biaxial testing of canine annulus fibrosus tissue under changing salt concentrations.
pubmed:affiliation
Department of Biomedical Engineering, Engineering Mechanics Institute, Eindhoven University of Technology, Eindhoven, The Netherlands. j.m.r.huyghe@tue.nl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't