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rdf:type |
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lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0026336,
umls-concept:C0027627,
umls-concept:C0042071,
umls-concept:C0392756,
umls-concept:C0441655,
umls-concept:C0591833,
umls-concept:C0598934,
umls-concept:C0677930,
umls-concept:C0684249,
umls-concept:C1522492
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pubmed:issue |
6
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pubmed:dateCreated |
2010-3-8
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pubmed:abstractText |
Lung cancer is the most common malignancy in humans. Urokinase (uPA) plays a crucial role in carcinogenesis by facilitating tumor cell invasion and metastasis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1535-4970
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pubmed:author |
pubmed-author:GüntherAndreasA,
pubmed-author:GreschusSusanneS,
pubmed-author:HennekeIngridI,
pubmed-author:KorfeiMartinaM,
pubmed-author:MahavadiPoornimaP,
pubmed-author:MarkartPhilippP,
pubmed-author:RuppertClemensC,
pubmed-author:SavaiRajkumarR,
pubmed-author:SchermulyRalph TRT,
pubmed-author:SeegerWernerW,
pubmed-author:StürzebecherJörgJ,
pubmed-author:WygreckaMalgorzataM
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
181
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
611-9
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pubmed:meshHeading |
pubmed-meshheading:20056905-Animals,
pubmed-meshheading:20056905-Benzamidines,
pubmed-meshheading:20056905-Blotting, Western,
pubmed-meshheading:20056905-Carcinoma, Lewis Lung,
pubmed-meshheading:20056905-Cell Culture Techniques,
pubmed-meshheading:20056905-Cell Proliferation,
pubmed-meshheading:20056905-Cone-Beam Computed Tomography,
pubmed-meshheading:20056905-Disease Models, Animal,
pubmed-meshheading:20056905-Dose-Response Relationship, Drug,
pubmed-meshheading:20056905-Enzyme Inhibitors,
pubmed-meshheading:20056905-Humans,
pubmed-meshheading:20056905-Lung,
pubmed-meshheading:20056905-Male,
pubmed-meshheading:20056905-Mice,
pubmed-meshheading:20056905-Mice, Inbred C57BL,
pubmed-meshheading:20056905-Mice, SCID,
pubmed-meshheading:20056905-Small Cell Lung Carcinoma,
pubmed-meshheading:20056905-Sodium Chloride,
pubmed-meshheading:20056905-Treatment Outcome,
pubmed-meshheading:20056905-Tumor Burden,
pubmed-meshheading:20056905-Urokinase-Type Plasminogen Activator
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pubmed:year |
2010
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pubmed:articleTitle |
Inhibition of urokinase activity reduces primary tumor growth and metastasis formation in a murine lung carcinoma model.
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pubmed:affiliation |
Universty of Giessen Lung Center, Dept. of Internal Medicine, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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