Linked Life Data

1986376

Source:http://linkedlifedata.com/resource/pubmed/id/1986376

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:1986376rdf:typepubmed:Citationlld:pubmed
pubmed-article:1986376lifeskim:mentionsumls-concept:C0025914lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0026809lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0242275lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0929301lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0040688lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0205245lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C1512083lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0026559lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0017262lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C2911684lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0871161lld:lifeskim
pubmed-article:1986376lifeskim:mentionsumls-concept:C0185117lld:lifeskim
pubmed-article:1986376pubmed:issue1lld:pubmed
pubmed-article:1986376pubmed:dateCreated1991-2-14lld:pubmed
pubmed-article:1986376pubmed:abstractTextPrimer-directed enzyme amplification was used to examine epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha) mRNA transcripts in mammary glands of young virgin, mature virgin, midpregnant, and midlactating mice. Transcripts for both EGF and TGF-alpha mRNA were detected in virgin and pregnant mice, whereas transcripts for EGF mRNA but not TGF-alpha mRNA were expressed in 10-day lactating mice. TGF-alpha was localized in the epithelial cap-cell layer of the advancing terminal end bud and in the stromal fibroblasts at the base of the terminal end bud; EGF was localized in the inner layers of the terminal end bud and in ductal cells of mammary epithelium. Implantation of pellets containing EGF or TGF-alpha into the regressed mammary gland of ovariectomized mice stimulated the reappearance of end buds; contralateral glands implanted with pellets containing albumin or insulin were not affected. These results indicate that an EGF-receptor-mediated pathway remained intact in the mammary gland epithelium in the absence of ovarian steroids and that local availability of either EGF or TGF-alpha is sufficient to stimulate the pattern of normal ductal growth. The detection of EGF and TFF-alpha transcripts at different stages of mammary gland development and the different patterns of immunolocalization suggest that each polypeptide plays a different role in normal mammary gland morphogenesis.lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:languageenglld:pubmed
pubmed-article:1986376pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:citationSubsetIMlld:pubmed
pubmed-article:1986376pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1986376pubmed:statusMEDLINElld:pubmed
pubmed-article:1986376pubmed:monthJanlld:pubmed
pubmed-article:1986376pubmed:issn0027-8424lld:pubmed
pubmed-article:1986376pubmed:authorpubmed-author:DiAugustineR...lld:pubmed
pubmed-article:1986376pubmed:authorpubmed-author:SnedekerS MSMlld:pubmed
pubmed-article:1986376pubmed:authorpubmed-author:BrownC FCFlld:pubmed
pubmed-article:1986376pubmed:issnTypePrintlld:pubmed
pubmed-article:1986376pubmed:day1lld:pubmed
pubmed-article:1986376pubmed:volume88lld:pubmed
pubmed-article:1986376pubmed:ownerNLMlld:pubmed
pubmed-article:1986376pubmed:authorsCompleteYlld:pubmed
pubmed-article:1986376pubmed:pagination276-80lld:pubmed
pubmed-article:1986376pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
pubmed-article:1986376pubmed:meshHeadingpubmed-meshheading:1986376-...lld:pubmed
More...