Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2009-6-24
pubmed:abstractText
Mass spectrometry (MS) in combination with liquid chromatography (LC), i.e. LC-MS, is the key analytical technique on which the emerging "omics" technologies of proteomics, metabolomics and lipidomics are based. It provides both structural and quantitative data and can be used in a "global" or "targeted" manner allowing on the one hand the identification of thousands of proteins from a tissue, or on the other the detection of biologically active metabolites at levels of a few parts-per-billion. It can be expected that the continued incremental developments in LC-MS along with data-handling routines will soon bear fruit in the quest for a greater understanding of human disease, leading to new drug targets and therapies. This tutorial review on proteomics, metabolomics and lipidomics will be of interest to the biochemical, biomedical and pharmaceutical communities, as well as those working in other branches of analytical bioscience.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0306-0012
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1882-96
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Mass spectrometry: from proteomics to metabolomics and lipidomics.
pubmed:affiliation
Institute of Mass Spectrometry, School of Medicine, Swansea University, Singleton Park, Swansea, UK SA2 8PP. w.j.griffiths@swansea.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't