rdf:type |
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0027051,
umls-concept:C0030705,
umls-concept:C0086045,
umls-concept:C0087086,
umls-concept:C0167627,
umls-concept:C0205225,
umls-concept:C0288672,
umls-concept:C0348016,
umls-concept:C0522523,
umls-concept:C0595454,
umls-concept:C0700198,
umls-concept:C1522318,
umls-concept:C1749467
|
pubmed:issue |
2
|
pubmed:dateCreated |
2009-10-5
|
pubmed:abstractText |
CD40 ligand has been suggested to play a pathogenic role in atherogenesis and coronary artery disease progression. Clinical studies suggest that intravenous (IV) abciximab administration attenuates the acute inflammatory response associated with percutaneous coronary intervention (PCI). The anti-inflammatory effects of intracoronary (IC) versus IV administration of abciximab have not been systematically investigated. We assessed changes in soluble CD40 ligand (sCD40L) concentrations in response to IC versus IV abciximab in patients with ST-elevation myocardial infarction (STEMI) undergoing thrombus-aspirating device during primary PCI.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1879-1484
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
206
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
523-7
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:19380134-Aged,
pubmed-meshheading:19380134-Aged, 80 and over,
pubmed-meshheading:19380134-Angioplasty, Balloon, Coronary,
pubmed-meshheading:19380134-Anti-Inflammatory Agents,
pubmed-meshheading:19380134-Antibodies, Monoclonal,
pubmed-meshheading:19380134-CD40 Ligand,
pubmed-meshheading:19380134-Female,
pubmed-meshheading:19380134-Humans,
pubmed-meshheading:19380134-Immunoglobulin Fab Fragments,
pubmed-meshheading:19380134-Infusions, Intravenous,
pubmed-meshheading:19380134-Injections, Intralesional,
pubmed-meshheading:19380134-Injections, Intravenous,
pubmed-meshheading:19380134-Male,
pubmed-meshheading:19380134-Middle Aged,
pubmed-meshheading:19380134-Myocardial Infarction,
pubmed-meshheading:19380134-Thrombosis,
pubmed-meshheading:19380134-Treatment Outcome
|
pubmed:year |
2009
|
pubmed:articleTitle |
Intracoronary versus intravenous abciximab administration in patients with ST-elevation myocardial infarction undergoing thrombus aspiration during primary percutaneous coronary intervention--effects on soluble CD40 ligand concentrations.
|
pubmed:affiliation |
Department of Cardiology, University Hospital of Canarias, Tenerife, Spain. adrvdg@hotmail.com
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
|