|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001565,
umls-concept:C0022614,
umls-concept:C0027796,
umls-concept:C0034656,
umls-concept:C0150097,
umls-concept:C0439611,
umls-concept:C0442027,
umls-concept:C0524527,
umls-concept:C1527148,
umls-concept:C2607943,
umls-concept:C2926606
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2009-4-15
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|
pubmed:abstractText |
Enterally administered low-dose ketamine is being used increasingly to treat pain states. However, suitable oral or sublingual formulations are not available. The objective of the study was to develop a lozenge formulation of ketamine for use in patients with neuropathic pain, and to investigate its storage stability and bioavailability after oral or sublingual administration.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1173-2563
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
317-24
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pubmed:meshHeading |
pubmed-meshheading:19366273-Administration, Oral,
pubmed-meshheading:19366273-Administration, Sublingual,
pubmed-meshheading:19366273-Adult,
pubmed-meshheading:19366273-Aged,
pubmed-meshheading:19366273-Analgesics,
pubmed-meshheading:19366273-Area Under Curve,
pubmed-meshheading:19366273-Biological Availability,
pubmed-meshheading:19366273-Chromatography, High Pressure Liquid,
pubmed-meshheading:19366273-Chronic Disease,
pubmed-meshheading:19366273-Cross-Over Studies,
pubmed-meshheading:19366273-Drug Stability,
pubmed-meshheading:19366273-Drug Storage,
pubmed-meshheading:19366273-Excitatory Amino Acid Antagonists,
pubmed-meshheading:19366273-Female,
pubmed-meshheading:19366273-Humans,
pubmed-meshheading:19366273-Ketamine,
pubmed-meshheading:19366273-Male,
pubmed-meshheading:19366273-Middle Aged,
pubmed-meshheading:19366273-Neuralgia,
pubmed-meshheading:19366273-Temperature
|
|
pubmed:year |
2009
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|
pubmed:articleTitle |
Development of a sublingual/oral formulation of ketamine for use in neuropathic pain: Preliminary findings from a three-way randomized, crossover study.
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|
pubmed:affiliation |
Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Western Australia, Australia.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
