Cross-Over Studies

Source:http://linkedlifedata.com/resource/umls/id/C0150097

MCM: A method of comparing two or more treatments or interventions in which subjects or patients, upon completion of the course of one treatment, are switched to another. Typically, allocation to the first treatment is by random process. Participants' performance in one period is used to judge their performance in others, usually reducing variability.,MSH: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed),NCI: A type of clinical study in which each study subject receives the same series of treatments but in a random order that differs across arms of the study. Each subject s

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