rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-3-25
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pubmed:abstractText |
To determine whether the promoter polymorphism tumor necrosis factor (TNF) (-308) is associated with susceptibility to or death from meningococcal sepsis. DESIGN, SETTING, PATIENTS, AND PARTICIPANTS: Association study involving 1321 patients with microbiologically proven invasive meningococcal disease presenting to hospitals throughout United Kingdom during 1998-2001, among whom 134 died. Controls were derived from 1280 northern English blood donors.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
1530-0293
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
37
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1237-43
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pubmed:meshHeading |
pubmed-meshheading:19242354-Adolescent,
pubmed-meshheading:19242354-Adult,
pubmed-meshheading:19242354-Aged,
pubmed-meshheading:19242354-Aged, 80 and over,
pubmed-meshheading:19242354-Child,
pubmed-meshheading:19242354-Child, Preschool,
pubmed-meshheading:19242354-Female,
pubmed-meshheading:19242354-Genetic Predisposition to Disease,
pubmed-meshheading:19242354-Genotype,
pubmed-meshheading:19242354-Humans,
pubmed-meshheading:19242354-Infant,
pubmed-meshheading:19242354-Male,
pubmed-meshheading:19242354-Meningococcal Infections,
pubmed-meshheading:19242354-Middle Aged,
pubmed-meshheading:19242354-Polymorphism, Genetic,
pubmed-meshheading:19242354-Sepsis,
pubmed-meshheading:19242354-Tumor Necrosis Factor-alpha,
pubmed-meshheading:19242354-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
The tumor necrosis factor polymorphism TNF (-308) is associated with susceptibility to meningococcal sepsis, but not with lethality.
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pubmed:affiliation |
Section of Infection, Inflammation and Immunity, University of Sheffield Medical School, Sheffield, United Kingdom. r.c.read@sheffield.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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