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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-11-2
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pubmed:abstractText |
Elevated levels of plasminogen activator inhibitor-1 (PAI-1), the major inhibitor of fibrinolysis, is associated with coronary artery disease (CAD). This association may not be independent of factors related to insulin resistance (IR). Patients with Type 1 diabetes mellitus have increased CAD and an increase in sub-clinical CAD which develops earlier in life. It is not known if PAI-1 is associated with sub-clinical CAD in Type 1 diabetes or if this association is independent of IR.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1873-460X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
387-93
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pubmed:meshHeading |
pubmed-meshheading:18768333-Adult,
pubmed-meshheading:18768333-Calcinosis,
pubmed-meshheading:18768333-Cohort Studies,
pubmed-meshheading:18768333-Coronary Artery Disease,
pubmed-meshheading:18768333-Diabetes Mellitus, Type 1,
pubmed-meshheading:18768333-Diabetic Angiopathies,
pubmed-meshheading:18768333-Disease Progression,
pubmed-meshheading:18768333-Female,
pubmed-meshheading:18768333-Humans,
pubmed-meshheading:18768333-Insulin Resistance,
pubmed-meshheading:18768333-Logistic Models,
pubmed-meshheading:18768333-Male,
pubmed-meshheading:18768333-Middle Aged,
pubmed-meshheading:18768333-Plasminogen Activator Inhibitor 1,
pubmed-meshheading:18768333-Risk Factors,
pubmed-meshheading:18768333-Young Adult
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pubmed:articleTitle |
Plasminogen activator inhibitor-1 is associated with coronary artery calcium in Type 1 diabetes.
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pubmed:affiliation |
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Denver, CO 80262, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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