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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-8-27
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pubmed:abstractText |
Besides the central role of the adaptive immune system, a disturbance of innate immunity is also involved in the pathogenesis of celiac disease (CD). Inasmuch as CD and type 1 diabetes mellitus (T1DM) frequently coexist because of a common genetic predisposition, our aim was to study the frequency of CD14 C-260T and TLR4 A+896G single nucleotide polymorphisms (SNPs) and the distribution of HLA-DQ genotypes in children affected by CD, T1DM, or both.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1536-4801
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pubmed:author |
pubmed-author:AratóAA,
pubmed-author:DezsofiAA,
pubmed-author:HermannC SCS,
pubmed-author:KörnerAA,
pubmed-author:KapitányAA,
pubmed-author:Korponay-SzabóII,
pubmed-author:MadácsyLL,
pubmed-author:RajczyKK,
pubmed-author:SipkaSS,
pubmed-author:SzebeniBB,
pubmed-author:VeresGG
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pubmed:issnType |
Electronic
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-7
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pubmed:meshHeading |
pubmed-meshheading:18728522-Adolescent,
pubmed-meshheading:18728522-Antigens, CD14,
pubmed-meshheading:18728522-Celiac Disease,
pubmed-meshheading:18728522-Child,
pubmed-meshheading:18728522-Child, Preschool,
pubmed-meshheading:18728522-Comorbidity,
pubmed-meshheading:18728522-Diabetes Mellitus, Type 1,
pubmed-meshheading:18728522-Female,
pubmed-meshheading:18728522-Gene Frequency,
pubmed-meshheading:18728522-Genetic Predisposition to Disease,
pubmed-meshheading:18728522-Genotype,
pubmed-meshheading:18728522-HLA-DQ Antigens,
pubmed-meshheading:18728522-Humans,
pubmed-meshheading:18728522-Male,
pubmed-meshheading:18728522-Polymerase Chain Reaction,
pubmed-meshheading:18728522-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:18728522-Polymorphism, Single Nucleotide,
pubmed-meshheading:18728522-Toll-Like Receptor 4,
pubmed-meshheading:18728522-Young Adult
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pubmed:year |
2008
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pubmed:articleTitle |
Frequencies of genetic polymorphisms of TLR4 and CD14 and of HLA-DQ genotypes in children with celiac disease, type 1 diabetes mellitus, or both.
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pubmed:affiliation |
First Department of Pediatrics, Semmelweis University, Hungary. antald@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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