HLA-DQ Antigens

Source:http://linkedlifedata.com/resource/umls/id/C0019761

MSH: A group of the D-related HLA antigens found to differ from the DR antigens in genetic locus and therefore inheritance. These antigens are polymorphic glycoproteins comprising alpha and beta chains and are found on lymphoid and other cells, often associated with certain diseases.,NCI: HLA-DQ antigen is a class of glycoproteins that consist of dimers of alpha and beta subunits, which are encoded by the polymorphic human genes HLA-DQA1 and HLA-DQB1, respectively. This protein complex is expressed primarily in lymphoid cells and function to present antigens for CD4+ T lymphocytes. Certain HLA-DQ protein variants are associated with susceptibility to insulin-dependent diabetes mellitus and several autoimmune diseases.

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