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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1976-12-30
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pubmed:abstractText |
Progesterone receptor preparations from avian oviduct catalyze a pyrophosphate (PPi)-exchange reaction between ATP and 32P-labeled PPi. The reaction requires ATP exclusively and is Mn++-dependent. This enzyme activity is detectable in receptor preparations that have been purified extensively by chromatography on ATP-Sepharose and DEAE-Sephadex columns. Polyacrylamide gel electrophoresis of purified preparations reveals a comigration of [3H]progesterone-receptor complex and the enzyme activity. The PPi-exchange reaction is inhibited by both o-phenanthroline and rifamycin AF/013, which also block the nuclear binding of progesterone receptor. These findings indicate that progesterone receptor may be an enzyme or a subunit of an enzyme that is active in nucleotide metabolism.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-10793710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-1092679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-1093181,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-1164499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-13819354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-14114840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-165193,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-165493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-16744823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-167742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-169895,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-173315,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4128882,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4304249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4305463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4306290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4310829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4373468,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4516206,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-4601749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-5011045,
http://linkedlifedata.com/resource/pubmed/commentcorrection/185612-5019955
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3443-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:185612-Adenosine Triphosphate,
pubmed-meshheading:185612-Animals,
pubmed-meshheading:185612-Chickens,
pubmed-meshheading:185612-Diphosphates,
pubmed-meshheading:185612-Female,
pubmed-meshheading:185612-Manganese,
pubmed-meshheading:185612-Oviducts,
pubmed-meshheading:185612-Phenanthrolines,
pubmed-meshheading:185612-Receptors, Progesterone,
pubmed-meshheading:185612-Rifamycins
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pubmed:year |
1976
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pubmed:articleTitle |
ATP-PPi exchange activity of progesterone receptor.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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