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rdf:type |
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lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0027059,
umls-concept:C0384648,
umls-concept:C0439849,
umls-concept:C0443146,
umls-concept:C0445223,
umls-concept:C1171362,
umls-concept:C1515926,
umls-concept:C1517004,
umls-concept:C1517499,
umls-concept:C1533585,
umls-concept:C1552599,
umls-concept:C1704787
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pubmed:issue |
5
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pubmed:dateCreated |
2008-4-28
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pubmed:abstractText |
T-helper (Th)1/Th2 cytokine balance plays an important role in the pathogenesis of myocarditis. Recently, some studies indicate that interleukin (IL)-17, known as a T cell (Th17)-derived proinflammatory cytokine, is the major mediator of tissue inflammation in inflammatory and autoimmune diseases. Experimental autoimmune myocarditis (EAM) is a T cell-mediated autoimmune disease; however, the pathogenic role of IL-17 in the development of rat EAM remains largely unknown.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-17,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-23,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-17,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1346-9843
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pubmed:author |
pubmed-author:AizawaYoshifusaY,
pubmed-author:HanawaHaruoH,
pubmed-author:HaoKazuhisaK,
pubmed-author:HayashiManabuM,
pubmed-author:HeChangC,
pubmed-author:KUOH YHY,
pubmed-author:KatoKiminoriK,
pubmed-author:KodamaMakotoM,
pubmed-author:LiminDingD,
pubmed-author:MaruyamaHirokiH,
pubmed-author:MiyazakiJunichiJ,
pubmed-author:OtakiKeitaK,
pubmed-author:TurkG MGM,
pubmed-author:YoshidaKaoriK,
pubmed-author:YoshidaTsuyoshiT
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pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
813-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18441464-Animals,
pubmed-meshheading:18441464-Autoimmune Diseases,
pubmed-meshheading:18441464-Cardiomyopathies,
pubmed-meshheading:18441464-Cells, Cultured,
pubmed-meshheading:18441464-Disease Models, Animal,
pubmed-meshheading:18441464-Gene Expression,
pubmed-meshheading:18441464-Gene Therapy,
pubmed-meshheading:18441464-Immunoglobulins,
pubmed-meshheading:18441464-Interferon-gamma,
pubmed-meshheading:18441464-Interleukin-10,
pubmed-meshheading:18441464-Interleukin-17,
pubmed-meshheading:18441464-Interleukin-23,
pubmed-meshheading:18441464-Male,
pubmed-meshheading:18441464-Myocarditis,
pubmed-meshheading:18441464-RNA, Messenger,
pubmed-meshheading:18441464-Rats,
pubmed-meshheading:18441464-Rats, Inbred Lew,
pubmed-meshheading:18441464-Receptors, Interleukin,
pubmed-meshheading:18441464-Receptors, Interleukin-17,
pubmed-meshheading:18441464-Recombinant Fusion Proteins,
pubmed-meshheading:18441464-Spleen,
pubmed-meshheading:18441464-Th1 Cells,
pubmed-meshheading:18441464-Th2 Cells
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pubmed:year |
2008
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pubmed:articleTitle |
Alteration of IL-17 related protein expressions in experimental autoimmune myocarditis and inhibition of IL-17 by IL-10-Ig fusion gene transfer.
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pubmed:affiliation |
Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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