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rdf:type |
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lifeskim:mentions |
umls-concept:C0023810,
umls-concept:C0024109,
umls-concept:C0024264,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0030190,
umls-concept:C0205191,
umls-concept:C0271510,
umls-concept:C0376618,
umls-concept:C1334114,
umls-concept:C1514559
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pubmed:issue |
12
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pubmed:dateCreated |
2007-11-23
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pubmed:abstractText |
Plasma plasminogen activator inhibitor-1 (PAI-1) level rises during sepsis and confers a worse prognosis. PAI-1 participation to sepsis has been poorly documented and was mainly associated with fibrin deposits. Beside fibrin deposits, increased tissue PAI-1 expression may contribute to the poor outcome of endotoxemia through other mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA-4 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Ccl3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL3,
http://linkedlifedata.com/resource/pubmed/chemical/Ctla4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Fibrin,
http://linkedlifedata.com/resource/pubmed/chemical/Forkhead Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Foxp3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Glucocorticoid-Induced...,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2 Receptor alpha Subunit,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Nerve Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Serpin E2,
http://linkedlifedata.com/resource/pubmed/chemical/Serpine2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Serpins,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfrsf18 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/lipopolysaccharide, E. coli 026-B6
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1538-7933
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2467-75
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17848179-Animals,
pubmed-meshheading:17848179-Antigens, CD,
pubmed-meshheading:17848179-Antigens, Differentiation,
pubmed-meshheading:17848179-CTLA-4 Antigen,
pubmed-meshheading:17848179-Chemokine CCL3,
pubmed-meshheading:17848179-Chemotaxis, Leukocyte,
pubmed-meshheading:17848179-Disease Models, Animal,
pubmed-meshheading:17848179-Endotoxemia,
pubmed-meshheading:17848179-Fibrin,
pubmed-meshheading:17848179-Forkhead Transcription Factors,
pubmed-meshheading:17848179-Glucocorticoid-Induced TNFR-Related Protein,
pubmed-meshheading:17848179-Immunity, Innate,
pubmed-meshheading:17848179-Inflammation,
pubmed-meshheading:17848179-Interferon-gamma,
pubmed-meshheading:17848179-Interleukin-2 Receptor alpha Subunit,
pubmed-meshheading:17848179-Interleukin-6,
pubmed-meshheading:17848179-Lipopolysaccharides,
pubmed-meshheading:17848179-Lung,
pubmed-meshheading:17848179-Macrophages,
pubmed-meshheading:17848179-Mice,
pubmed-meshheading:17848179-Mice, Knockout,
pubmed-meshheading:17848179-Mice, Transgenic,
pubmed-meshheading:17848179-Neutrophils,
pubmed-meshheading:17848179-Pulmonary Fibrosis,
pubmed-meshheading:17848179-RNA, Messenger,
pubmed-meshheading:17848179-Receptors, Nerve Growth Factor,
pubmed-meshheading:17848179-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:17848179-Serpin E2,
pubmed-meshheading:17848179-Serpins,
pubmed-meshheading:17848179-T-Lymphocytes,
pubmed-meshheading:17848179-T-Lymphocytes, Regulatory,
pubmed-meshheading:17848179-Time Factors,
pubmed-meshheading:17848179-Up-Regulation
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pubmed:year |
2007
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pubmed:articleTitle |
Chronic plasminogen activator inhibitor-1 (PAI-1) overexpression dampens CD25+ lymphocyte recruitment after lipopolysaccharide endotoxemia in mouse lung.
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pubmed:affiliation |
Faculté de Médecine, Aix-Marseille Université, Marseille, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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