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pubmed:abstractText |
Palytoxin (PLT) is a potent toxin that binds to the Na,K-ATPase. Palytoxin is highly neurotoxic and increases the cytosolic calcium concentration ([Ca(2+)](c)) while decreasing intracellular pH (pH(i)) in neurons (Vale et al., 2006; Vale-Gonzalez et al., 2007). It is also a tumour promoter that activates several protein kinases.
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pubmed:affiliation |
Departamento de Farmacología, Facultad de Veterinaria, USC, Campus Universitario s/n, Lugo, Spain.
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