Linked Life Data

17466595

Source:http://linkedlifedata.com/resource/pubmed/id/17466595

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-6-1
pubmed:abstractText
Despite the major biological importance of perforin as a mediator of antiviral and anticancer immunity, the cis regulatory elements on mouse or human chromosome 10 that control perforin gene (PRF1) expression have long eluded our understanding. In a recent study of near-Herculean proportions, Pipkin, Lichtenheld and colleagues at the University of Miami have now defined both the functional boundaries of human PRF1, and identified the probable locus control region that bestows both cell lineage- and IL-2- and TCR-specific gene expression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1471-4906
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-5
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
The complex issue of regulating perforin expression.
pubmed:affiliation
Cancer Immunology Program, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, 3002, Australia. joe.trapani@petermac.org
pubmed:publicationType
Journal Article, Review