Linked Life Data

16904732

Source:http://linkedlifedata.com/resource/pubmed/id/16904732

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-11-22
pubmed:abstractText
Since the appearance of DDT, increasingly potent insecticides have been developed to overcome the resistance developed by insects to successive products. Pesticides are also used in public health programs to control disease vectors. Despite legislation to control the use of certain products, they repeatedly appear in the adipose tissue, milk and serum of human populations. The present study determined the presence of organochlorine molecules in the adipose tissue, serum, and umblical cord of women giving birth by cesarean section in order to establish a possible correlation in organochlorine molecule content between these biological compartments and to examine fetal exposure to molecules with hormonal effects. Presence of nine organochlorines was detected by GC/ECD and confirmed by GC/MS. Highly significant differences (p<0.000) were observed between adipose tissue and maternal serum in concentrations of lindane, HCB, DDE, DDD, and endosulfan but not (p>0.5) in concentrations of endosulfan II or endosulfan sulfate. Only DDE concentrations differed (p<0.001) between maternal serum and umbilical cord serum. An association between pp'DDE and op'DDT was observed in maternal serum (p<0.094). An association in pp'DDE and pp'DDD content was found between adipose tissue and umbilical cord serum, and in pp'DDT content between adipose tissue and maternal serum. Results obtained indicate that exposure can be measured solely in serum when relatively high concentrations of pesticides are present.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0048-9697
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
372
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
32-8
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Organochlorine pesticides in serum and adipose tissue of pregnant women in Southern Spain giving birth by cesarean section.
pubmed:affiliation
Department Nutrition and Food Science, School of Pharmacy, University of Granada, Spain.
pubmed:publicationType
Journal Article