Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-8-2
pubmed:abstractText
This study evaluated the compliance and stiffness of decellularized canine common carotid artery as well as decellularized canine ureter and compared it with that of polytetrafluoroethylene, elastin gel combined with polylactic acid tube, and canine common carotid artery. To calculate the compliance and stiffness, internal diameters and cross-sectional areas were measured according to changes in the intraluminal pressures using intravascular ultrasound in a closed circuit system equipped with a syringe pump. The pressure-area curve, stiffness parameter beta, and diameter compliance were evaluated. Canine common carotid artery and decellularized canine common carotid artery, as well as decellularized canine ureter, showed a compliant response, a J-shaped curve. However, the latter evidenced different characteristics in the low pressure range. Although the cross-sectional area of the elastin gel combined with polylactic acid tube showed some changes, it did not present a J-shape curve. Polytetrafluoroethylene exhibited a noncompliant response.The results in this study have shown that the compliance in the decellularized matrices was maintained after cell extraction, which demonstrated the importance of the remaining matrix structure in the mechanical properties of decellularized tissue. A clear difference between the decellularized matrices and synthetic materials was noted in terms of the compliance, even in materials composed of relatively elastic materials.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1058-2916
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
450-5
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:16883127-Animals, pubmed-meshheading:16883127-Biocompatible Materials, pubmed-meshheading:16883127-Biodegradation, Environmental, pubmed-meshheading:16883127-Bioprosthesis, pubmed-meshheading:16883127-Blood Vessel Prosthesis, pubmed-meshheading:16883127-Blood Vessel Prosthesis Implantation, pubmed-meshheading:16883127-Carotid Artery, Common, pubmed-meshheading:16883127-Compliance, pubmed-meshheading:16883127-Deoxycholic Acid, pubmed-meshheading:16883127-Detergents, pubmed-meshheading:16883127-Dogs, pubmed-meshheading:16883127-Elasticity, pubmed-meshheading:16883127-Elastin, pubmed-meshheading:16883127-Evaluation Studies as Topic, pubmed-meshheading:16883127-Gels, pubmed-meshheading:16883127-Lactic Acid, pubmed-meshheading:16883127-Nanotechnology, pubmed-meshheading:16883127-Polyethylene Terephthalates, pubmed-meshheading:16883127-Polymers, pubmed-meshheading:16883127-Tissue Engineering, pubmed-meshheading:16883127-Ultrasonics, pubmed-meshheading:16883127-Ureter
pubmed:articleTitle
Evaluation of compliance and stiffness of decellularized tissues as scaffolds for tissue-engineered small caliber vascular grafts using intravascular ultrasound.
pubmed:affiliation
Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't