Premature infants, especially those with birth weights of <1500 g, often suffer from anemia of prematurity and associated problems. Erythropoietin therapy is a safe effective way to prevent and to treat anemia of prematurity. We hypothesized that combined administration of vitamin B12 and folate with erythropoietin and iron would enhance erythropoietin-induced erythropoiesis.
Department of Pediatrics, Division of Neonatology, Inborn Errors, and Pediatric Intensive Care, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. nadja.haiden@meduniwien.ac.at