Source:http://linkedlifedata.com/resource/pubmed/id/16739218
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2006-9-21
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pubmed:abstractText |
Diagnostic evaluation of acute leukemia at Roswell Park Cancer Institute has routinely included immunophenotyping by multiparameter flow cytometry. In a retrospective analysis of 646 cases, morphology and cytochemistry established lineage in 612, but not in 34 (5%), of which 26, 5, and 3 were myeloid, undifferentiated, and lymphoid, respectively, based on immunophenotyping. In addition, immunophenotyping changed the lineage assigned based on morphology and cytochemistry in 11 cases (2%); 8 changed from lymphoid to myeloid, and 3 from myeloid to lymphoid. The data support routine inclusion of at least limited immunophenotyping in the diagnostic evaluation of acute leukemia.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1552-4949
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2006 International Society for Analytical Cytology.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
329-34
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pubmed:dateRevised |
2009-12-11
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pubmed:meshHeading |
pubmed-meshheading:16739218-Adult,
pubmed-meshheading:16739218-Antigens, CD,
pubmed-meshheading:16739218-Cell Lineage,
pubmed-meshheading:16739218-Flow Cytometry,
pubmed-meshheading:16739218-Humans,
pubmed-meshheading:16739218-Immunophenotyping,
pubmed-meshheading:16739218-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:16739218-Retrospective Studies,
pubmed-meshheading:16739218-Tumor Markers, Biological
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pubmed:year |
2006
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pubmed:articleTitle |
Routine immunophenotyping in acute leukemia: Role in lineage assignment and reassignment.
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pubmed:affiliation |
Leukemia Section, Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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