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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2006-4-26
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pubmed:abstractText |
To determine the role of the extracellular chaperone clusterin in the pathophysiology of pseudoexfoliation (PEX) syndrome/glaucoma, which is characterized by the stable deposition of abnormal extracellular fibrillar material in anterior segment tissues.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1982-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16639006-Aged,
pubmed-meshheading:16639006-Aged, 80 and over,
pubmed-meshheading:16639006-Anterior Eye Segment,
pubmed-meshheading:16639006-Blotting, Western,
pubmed-meshheading:16639006-Cell Culture Techniques,
pubmed-meshheading:16639006-Ciliary Body,
pubmed-meshheading:16639006-Clusterin,
pubmed-meshheading:16639006-Down-Regulation,
pubmed-meshheading:16639006-Epithelium,
pubmed-meshheading:16639006-Exfoliation Syndrome,
pubmed-meshheading:16639006-Extracellular Matrix,
pubmed-meshheading:16639006-Female,
pubmed-meshheading:16639006-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:16639006-Glaucoma, Angle-Closure,
pubmed-meshheading:16639006-Glaucoma, Open-Angle,
pubmed-meshheading:16639006-Humans,
pubmed-meshheading:16639006-In Situ Hybridization,
pubmed-meshheading:16639006-Male,
pubmed-meshheading:16639006-Pigment Epithelium of Eye,
pubmed-meshheading:16639006-RNA, Messenger,
pubmed-meshheading:16639006-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16639006-Transforming Growth Factor beta,
pubmed-meshheading:16639006-Transforming Growth Factor beta1
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pubmed:year |
2006
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pubmed:articleTitle |
Clusterin deficiency in eyes with pseudoexfoliation syndrome may be implicated in the aggregation and deposition of pseudoexfoliative material.
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pubmed:affiliation |
Department of Ophthalmology, University of Erlangen-Nürnberg, Erlangen, Germany. matthias.zenkel@augen.imed.uni-erlangen.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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